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Detecting diagnostic features in MS/MS spectra of post-translationally modified peptides

Post-translational modifications are an area of great interest in mass spectrometry-based proteomics, with a surge in methods to detect them in recent years. However, post-translational modifications can introduce complexity into proteomics searches by fragmenting in unexpected ways, ultimately hind...

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Detalles Bibliográficos
Autores principales: Geiszler, Daniel J., Polasky, Daniel A., Yu, Fengchao, Nesvizhskii, Alexey I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338467/
https://www.ncbi.nlm.nih.gov/pubmed/37438360
http://dx.doi.org/10.1038/s41467-023-39828-0