Personalised circulating tumour DNA assay with large-scale mutation coverage for sensitive minimal residual disease detection in colorectal cancer

BACKGROUND: Postoperative minimal residual disease (MRD) detection using circulating-tumour DNA (ctDNA) requires a highly sensitive analysis platform. We have developed a tumour-informed, hybrid-capture ctDNA sequencing MRD assay. METHODS: Personalised target-capture panels for ctDNA detection were...

Descripción completa

Detalles Bibliográficos
Autores principales: Ryoo, Seung-Bum, Heo, Sunghoon, Lim, Yoojoo, Lee, Wookjae, Cho, Su Han, Ahn, Jongseong, Kang, Jun-Kyu, Kim, Su Yeon, Kim, Hwang-Phill, Bang, Duhee, Kang, Sung-Bum, Yu, Chang Sik, Oh, Seong Taek, Park, Ji Won, Jeong, Seung-Yong, Kim, Young-Joon, Park, Kyu Joo, Han, Sae-Won, Kim, Tae-You
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338477/
https://www.ncbi.nlm.nih.gov/pubmed/37280413
http://dx.doi.org/10.1038/s41416-023-02300-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338477/
https://www.ncbi.nlm.nih.gov/pubmed/37280413
http://dx.doi.org/10.1038/s41416-023-02300-3

Ejemplares similares