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Personalised circulating tumour DNA assay with large-scale mutation coverage for sensitive minimal residual disease detection in colorectal cancer

BACKGROUND: Postoperative minimal residual disease (MRD) detection using circulating-tumour DNA (ctDNA) requires a highly sensitive analysis platform. We have developed a tumour-informed, hybrid-capture ctDNA sequencing MRD assay. METHODS: Personalised target-capture panels for ctDNA detection were...

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Detalles Bibliográficos
Autores principales:	Ryoo, Seung-Bum, Heo, Sunghoon, Lim, Yoojoo, Lee, Wookjae, Cho, Su Han, Ahn, Jongseong, Kang, Jun-Kyu, Kim, Su Yeon, Kim, Hwang-Phill, Bang, Duhee, Kang, Sung-Bum, Yu, Chang Sik, Oh, Seong Taek, Park, Ji Won, Jeong, Seung-Yong, Kim, Young-Joon, Park, Kyu Joo, Han, Sae-Won, Kim, Tae-You
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338477/ https://www.ncbi.nlm.nih.gov/pubmed/37280413 http://dx.doi.org/10.1038/s41416-023-02300-3

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