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Association between development of severe COVID-19 and a polymorphism in the CIAS1 gene that codes for an inflammasome component

An elevated pro-inflammatory cytokine response is associated with severe life-threatening symptoms in individuals with Coronavirus Disease-2019 (COVID). The inflammasome is an intracellular structure responsible for generation of interleukin (IL)-1β and IL-18. NALP3, a product of the CIAS1 gene, is...

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Detalles Bibliográficos
Autores principales: Tozetto-Mendoza, Tania R., Mendes-Correa, Maria Cassia, Linhares, Iara Moreno, de Cássia Raymundi, Vanessa, de oliveira Paião, Heuder Gustavo, Barbosa, Erick Matheus Garcia, Luna-Muschi, Alessandra, Honorato, Layla, Correa, Giovanna Francisco, da Costa, Antonio Charlys, Costa, Silvia Figueiredo, Witkin, Steven S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338506/
https://www.ncbi.nlm.nih.gov/pubmed/37438453
http://dx.doi.org/10.1038/s41598-023-38095-9