Turnover number predictions for kinetically uncharacterized enzymes using machine and deep learning

The turnover number k(cat), a measure of enzyme efficiency, is central to understanding cellular physiology and resource allocation. As experimental k(cat) estimates are unavailable for the vast majority of enzymatic reactions, the development of accurate computational prediction methods is highly d...

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Detalles Bibliográficos
Autores principales: Kroll, Alexander, Rousset, Yvan, Hu, Xiao-Pan, Liebrand, Nina A., Lercher, Martin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338564/
https://www.ncbi.nlm.nih.gov/pubmed/37438349
http://dx.doi.org/10.1038/s41467-023-39840-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338564/
https://www.ncbi.nlm.nih.gov/pubmed/37438349
http://dx.doi.org/10.1038/s41467-023-39840-4

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