Intraindividual Variability in Absolute Bioavailability and Clearance of Midazolam in Healthy Individuals

BACKGROUND AND OBJECTIVE: Midazolam is the preferred clinical probe drug for assessing CYP3A activity. We have previously shown substantial intraindividual variability in midazolam absolute bioavailability and clearance in patients with obesity before and after weight loss induced by gastric bypass...

Descripción completa

Detalles Bibliográficos
Autores principales: Kvitne, Kine Eide, Drevland, Ole Martin, Haugli, Nora, Skadberg, Eline, Zaré, Hasse Khiabani, Åsberg, Anders, Robertsen, Ida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338616/
https://www.ncbi.nlm.nih.gov/pubmed/37162619
http://dx.doi.org/10.1007/s40262-023-01257-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338616/
https://www.ncbi.nlm.nih.gov/pubmed/37162619
http://dx.doi.org/10.1007/s40262-023-01257-z

Ejemplares similares