Advancements in a FRET Biosensor for Live-Cell Fluorescence-Lifetime High-Throughput Screening of Alpha-Synuclein

There is a critical need for small molecules capable of rescuing pathophysiological phenotypes induced by alpha-synuclein (aSyn) misfolding and oligomerization. Building upon our previous aSyn cellular fluorescence lifetime (FLT)-Förster resonance energy transfer (FRET) biosensors, we have developed...

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Detalles Bibliográficos
Autores principales: Braun, Anthony R., Kochen, Noah Nathan, Yuen, Samantha L., Liao, Elly E., Cornea, Razvan L., Thomas, David D., Sachs, Jonathan N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338669/
https://www.ncbi.nlm.nih.gov/pubmed/37428128
http://dx.doi.org/10.1177/17590914231184086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338669/
https://www.ncbi.nlm.nih.gov/pubmed/37428128
http://dx.doi.org/10.1177/17590914231184086

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