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In vitro Selection and in vivo Testing of Riboswitch-inspired Aptamers

Engineered aptamers for new compounds are typically produced by using in vitro selection methods. However, aptamers that are developed in vitro might not function as expected when introduced into complex cellular environments. One approach that addresses this concern is the design of initial RNA poo...

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Detalles Bibliográficos
Autores principales: Mohsen, Michael G., Breaker, Ronald R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bio-Protocol 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338711/
https://www.ncbi.nlm.nih.gov/pubmed/37456339
http://dx.doi.org/10.21769/BioProtoc.4775