mRNA Delivery Platform Based on Bacterial Outer Membrane Vesicles for Tumor Vaccine

The rapid display and delivery method for customized tumor mRNA vaccines is limited. Herein, bacteria-derived outer membrane vesicles (OMVs) are employed as an mRNA delivery platform by surface engineering of an RNA-binding protein, L7Ae. OMV-L7Ae can rapidly adsorb boxC/D sequence-labeled mRNA anti...

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Detalles Bibliográficos
Autores principales: Gao, Xiaoyu, Li, Yao, Nie, Guangjun, Zhao, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bio-Protocol 2023
Materias:
Methods Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338712/
https://www.ncbi.nlm.nih.gov/pubmed/37456344
http://dx.doi.org/10.21769/BioProtoc.4774

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338712/
https://www.ncbi.nlm.nih.gov/pubmed/37456344
http://dx.doi.org/10.21769/BioProtoc.4774

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