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Transcriptome-wide RNA binding analysis of C9orf72 poly(PR) dipeptides

An intronic GGGGCC repeat expansion in C9orf72 is a common genetic cause of amyotrophic lateral sclerosis and frontotemporal dementia. The repeats are transcribed in both sense and antisense directions to generate distinct dipeptide repeat proteins, of which poly(GA), poly(GR), and poly(PR) have bee...

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Detalles Bibliográficos
Autores principales: Balendra, Rubika, Ruiz de los Mozos, Igor, Odeh, Hana M, Glaria, Idoia, Milioto, Carmelo, Wilson, Katherine M, Ule, Agnieszka M, Hallegger, Martina, Masino, Laura, Martin, Stephen, Patani, Rickie, Shorter, James, Ule, Jernej, Isaacs, Adrian M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338859/
https://www.ncbi.nlm.nih.gov/pubmed/37438085
http://dx.doi.org/10.26508/lsa.202201824