Cargando…

mRNA-based SARS-CoV-2 Comirnaty vaccine elicits weak and short specific memory B cell response in individuals with no previous infection

OBJECTIVES: The dynamics of the memory B cell (MBC) repertoire after SARS-CoV-2 vaccination is crucial for assessing long-term immunity. We compare spike-specific MBC responses between SARS-CoV-2 unexposed and recovered individuals, and their impact on breakthrough infections during follow-up. METHO...

Descripción completa

Detalles Bibliográficos
Autores principales: Casado, José L., Vizcarra, Pilar, Martín-Hondarza, Adrián, Gómez-Maldonado, Sandra, Muedra-Sánchez, Magdalena, del Pino, Judith, Mirabella, Itria G., Martín-Colmenarejo, Sara, Haemmerle, Johannes, Fernández-Escribano, Marina, Vallejo, Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338867/
https://www.ncbi.nlm.nih.gov/pubmed/37457694
http://dx.doi.org/10.3389/fimmu.2023.1127379