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The impact of TP53 activation and apoptosis in primary hereditary microcephaly

Autosomal recessive primary microcephaly (MCPH) is a constellation of disorders that share significant brain size reduction and mild to moderate intellectual disability, which may be accompanied by a large variety of more invalidating clinical signs. Extensive neural progenitor cells (NPC) prolifera...

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Detalles Bibliográficos
Autores principales: Iegiani, Giorgia, Ferraro, Alessia, Pallavicini, Gianmarco, Di Cunto, Ferdinando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338886/
https://www.ncbi.nlm.nih.gov/pubmed/37457016
http://dx.doi.org/10.3389/fnins.2023.1220010