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Eurycomanone stimulates bone mineralization in zebrafish larvae and promotes osteogenic differentiation of mesenchymal stem cells by upregulating AKT/GSK-3β/β-catenin signaling

BACKGROUND: Eurycomanone (EN) is a diterpenoid compound isolated from the roots of Eurycoma longifolia (E. longifolia). Previous studies have confirmed that E. longifolia can enhance bone regeneration and bone strength. We previously isolated and identified ten quassinoids from E. longifolia, and th...

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Detalles Bibliográficos
Autores principales: Zhong, Yan-ting, Liao, Hong-bo, Ye, Zhi-qiang, Jiang, Hua-sheng, Li, Jia-xiao, Ke, Lin-mao, Hua, Jun-ying, Wei, Bo, Wu, Xin, Cui, Liao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Speaking Orthopaedic Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338906/
https://www.ncbi.nlm.nih.gov/pubmed/37457309
http://dx.doi.org/10.1016/j.jot.2023.05.006