Gli1 depletion induces oxidative stress and apoptosis of nucleus pulposus cells via Fos in intervertebral disc degeneration

BACKGROUND: Intervertebral disc degeneration (IDD) is the most common chronic disease. Oxidative stress and apoptosis of nucleus pulposus (NP) cells disrupt intervertebral disc (IVD) homeostasis, which is the main cause of IDD. Glioma-associated oncogene 1 (Gli1) is an important transcription factor...

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Detalles Bibliográficos
Autores principales: Liu, Libangxi, Zhang, Yuyao, Fu, Jiawei, Ai, Xuezheng, Long, Dan, Leng, Xue, Zhang, Yang, Huang, Bo, Li, Changqing, Zhou, Yue, Feng, Chencheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Speaking Orthopaedic Society 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338909/
https://www.ncbi.nlm.nih.gov/pubmed/37457313
http://dx.doi.org/10.1016/j.jot.2023.05.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10338909/
https://www.ncbi.nlm.nih.gov/pubmed/37457313
http://dx.doi.org/10.1016/j.jot.2023.05.008

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