Breast cancer PDxO cultures for drug discovery and functional precision oncology

Patient-derived xenografts (PDXs) have clinical value but are time-, cost-, and labor-intensive and thus ill-suited for large-scale experiments. Here, we present a protocol to convert PDX tumors into PDxOs for long-term cultures amenable to moderate-throughput drug screens, including in-depth PDxO v...

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Detalles Bibliográficos
Autores principales: Scherer, Sandra D., Zhao, Ling, Butterfield, Andrew J., Yang, Chieh-Hsiang, Cortes-Sanchez, Emilio, Guillen, Katrin P., Welm, Bryan E., Welm, Alana L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10339058/
https://www.ncbi.nlm.nih.gov/pubmed/37402170
http://dx.doi.org/10.1016/j.xpro.2023.102402

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10339058/
https://www.ncbi.nlm.nih.gov/pubmed/37402170
http://dx.doi.org/10.1016/j.xpro.2023.102402

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