Effects of Leptin and Body Weight on Inflammation and Knee Osteoarthritis Phenotypes in Female Rats

Leptin is a proinflammatory adipokine that contributes to obesity‐associated osteoarthritis (OA), especially in women. However, the extent to which leptin causes knee OA separate from the effect of increased body weight is not clear. We hypothesized that leptin is necessary to induce knee OA in obes...

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Detalles Bibliográficos
Autores principales: Fu, Yao, Batushansky, Albert, Kinter, Michael, Huebner, Janet L., Kraus, Virginia B., Griffin, Timothy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10339097/
https://www.ncbi.nlm.nih.gov/pubmed/37457883
http://dx.doi.org/10.1002/jbm4.10754

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10339097/
https://www.ncbi.nlm.nih.gov/pubmed/37457883
http://dx.doi.org/10.1002/jbm4.10754

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