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Carnitine o-octanoyltransferase is a p53 target that promotes oxidative metabolism and cell survival following nutrient starvation

Whereas it is known that p53 broadly regulates cell metabolism, the specific activities that mediate this regulation remain partially understood. Here, we identified carnitine o-octanoyltransferase (CROT) as a p53 transactivation target that is upregulated by cellular stresses in a p53-dependent man...

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Detalles Bibliográficos
Autores principales: Sanford, Jack D., Franklin, Derek, Grois, Gabriella A., Jin, Aiwen, Zhang, Yanping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10339192/
https://www.ncbi.nlm.nih.gov/pubmed/37307919
http://dx.doi.org/10.1016/j.jbc.2023.104908