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Structural basis for recognition and methylation of p97 by METTL21D, a valosin-containing protein lysine methyltransferase

p97 is a human AAA+ (ATPase associated with diverse cellular activities, also known as valosin-containing protein [VCP]) ATPase, which is involved in diverse cellular processes such as membrane fusion and proteolysis. Lysine-specific methyltransferase of p97 (METTL21D) was identified as a class I me...

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Detalles Bibliográficos
Autores principales: Nguyen, Thang Quyet, Koh, Seri, Kwon, Jiin, Jang, Soyeon, Kang, Wonchull, Yang, Jin Kuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10339199/
https://www.ncbi.nlm.nih.gov/pubmed/37456834
http://dx.doi.org/10.1016/j.isci.2023.107222