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Breathing on chip: Dynamic flow and stretch accelerate mucociliary maturation of airway epithelium in vitro

Human lung function is intricately linked to blood flow and breathing cycles, but it remains unknown how these dynamic cues shape human airway epithelial biology. Here we report a state-of-the-art protocol for studying the effects of dynamic medium and airflow as well as stretch on human primary air...

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Detalles Bibliográficos
Autores principales: Nawroth, Janna C., Roth, Doris, van Schadewijk, Annemarie, Ravi, Abilash, Maulana, Tengku Ibrahim, Senger, Christiana N., van Riet, Sander, Ninaber, Dennis K., de Waal, Amy M., Kraft, Dorothea, Hiemstra, Pieter S., Ryan, Amy L., van der Does, Anne M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10339259/
https://www.ncbi.nlm.nih.gov/pubmed/37455819
http://dx.doi.org/10.1016/j.mtbio.2023.100713