Evaluation of Drug Responses to Human β(2)AR Using Native Mass Spectrometry

[Image: see text] We aimed to develop a platform to rapidly investigate the responses of agonists and antagonists to G-protein-coupled receptors (GPCRs) using native mass spectrometry (MS). We successfully observed the ligand-bound human β(2) adrenergic receptor (hβ(2)AR); however, it was challengin...

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Detalles Bibliográficos
Autores principales: Tajiri, Michiko, Imai, Shunsuke, Konuma, Tsuyoshi, Shimamoto, Keiko, Shimada, Ichio, Akashi, Satoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10339329/
https://www.ncbi.nlm.nih.gov/pubmed/37457453
http://dx.doi.org/10.1021/acsomega.3c02737

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10339329/
https://www.ncbi.nlm.nih.gov/pubmed/37457453
http://dx.doi.org/10.1021/acsomega.3c02737

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