Cargando…

Mitochondrial DNA methylation is a predictor of immunotherapy response and prognosis in breast cancer: scRNA-seq and bulk-seq data insights

BACKGROUND: Alterations in Mitochondrial DNA methylation (MTDM) exist in many tumors, but their role in breast cancer (BC) development remains unclear. METHODS: We analyzed BC patient data by combining scRNA-seq and bulk sequencing. Weighted co-expression network analysis (WGCNA) of TCGA data identi...

Descripción completa

Detalles Bibliográficos
Autores principales: Ma, Yixuan, Du, Juan, Chen, Meini, Gao, Ning, Wang, Sijia, Mi, Zhikuan, Wei, Xiaoli, Zhao, Jumei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10339346/
https://www.ncbi.nlm.nih.gov/pubmed/37457713
http://dx.doi.org/10.3389/fimmu.2023.1219652