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BMP4 upregulates glycogen synthesis through the SMAD/SLC2A1 (GLUT1) signaling axis in hepatocellular carcinoma (HCC) cells

BACKGROUND: Excessive hepatic glycogen accumulation benefits tumorigenesis and cancer cell survival. We previously reported that BMP4 has the strongest ability to promote glycogenesis among the 14 BMPs in hepatocytes and augmented hepatocellular carcinoma (HCC) cell survival under hypoxia and hypogl...

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Detalles Bibliográficos
Autores principales: Zhong, Jiamin, Tian, Luyao, Gou, Yannian, Zhao, Piao, Dong, Xiangyu, Guo, Meichun, Zhao, Guozhi, Li, Aohua, Hao, Ailing, He, Tong-Chuan, Fan, Jiaming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10339511/
https://www.ncbi.nlm.nih.gov/pubmed/37443106
http://dx.doi.org/10.1186/s40170-023-00310-6