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Balanced crystalloids (RInger’s lactate) versus normal Saline in adults with diabetic Ketoacidosis in the Emergency Department (BRISK-ED): a protocol for a pilot randomized controlled trial

BACKGROUND: Current guidelines for diabetic ketoacidosis (DKA) recommend treatment with normal saline (NS). However, NS, with its high chloride concentrations, may worsen acidosis and contribute to a hyperchloremic metabolic acidosis. Alternatives to NS are balanced crystalloids (e.g. Ringer’s Lacta...

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Detalles Bibliográficos
Autores principales: Yan, Justin W., Slim, Ahmed, Van Aarsen, Kristine, Choi, Yun-Hee, Byrne, Christopher, Poonai, Naveen, Collins, Haley, Clemens, Kristin K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10339541/
https://www.ncbi.nlm.nih.gov/pubmed/37443083
http://dx.doi.org/10.1186/s40814-023-01356-5