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Genetic inactivation of the Carnitine/Acetyl-Carnitine mitochondrial carrier of Yarrowia lipolytica leads to enhanced odd-chain fatty acid production

BACKGROUND: Mitochondrial carriers (MCs) can deeply affect the intracellular flux distribution of metabolic pathways. The manipulation of their expression level, to redirect the flux toward the production of a molecule of interest, is an attractive target for the metabolic engineering of eukaryotic...

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Detalles Bibliográficos
Autores principales: Messina, Eugenia, de Souza, Camilla Pires, Cappella, Claudia, Barile, Simona Nicole, Scarcia, Pasquale, Pisano, Isabella, Palmieri, Luigi, Nicaud, Jean-Marc, Agrimi, Gennaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10339547/
https://www.ncbi.nlm.nih.gov/pubmed/37443049
http://dx.doi.org/10.1186/s12934-023-02137-8