Indole-based FLT3 inhibitors and related scaffolds as potential therapeutic agents for acute myeloid leukemia

Fms-like tyrosine kinase 3 (FLT3) mutation mechanisms are among the most common genetic abnormalities detected in about 30% of acute myeloid leukemia (AML) patients. These mutations are accompanied by poor clinical response, although all these progressions in identifying and interpreting biological...

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Detalles Bibliográficos
Autores principales: Ezelarab, Hend A. A., Ali, Taha F. S., Abbas, Samar H., Hassan, Heba A., Beshr, Eman A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10339569/
https://www.ncbi.nlm.nih.gov/pubmed/37438819
http://dx.doi.org/10.1186/s13065-023-00981-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10339569/
https://www.ncbi.nlm.nih.gov/pubmed/37438819
http://dx.doi.org/10.1186/s13065-023-00981-8

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