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Screening and identification of emodin as an EBV DNase inhibitor to prevent its biological functions

BACKGROUND: The Epstein-Barr virus (EBV) is a prevalent oncovirus associated with a variety of human illnesses. BGLF5, an EBV DNase with alkaline nuclease (AN) activity, plays important roles in the viral life cycle and progression of human malignancies and has been suggested as a possible diagnosti...

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Detalles Bibliográficos
Autores principales: Wu, Chung-Chun, Chen, Mei-Shu, Lee, Ting-Ying, Cheng, Yu-Jhen, Tsou, Hsiao-Hui, Huang, Tze-Sing, Cho, Der-Yang, Chen, Jen-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10339607/
https://www.ncbi.nlm.nih.gov/pubmed/37443068
http://dx.doi.org/10.1186/s12985-023-02107-x