In vivo tissue pharmacokinetics of ERBB2‐specific binding oligonucleotide‐based drugs by PET imaging

Although aptamers have shown excellent target specificity in preclinical and clinical studies either by themselves or as aptamer‐drug conjugates, their in vivo tissue pharmacokinetic (PK) analysis is still problematic. We aimed to examine the utility of image‐based positron emission tomography (PET)...

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Detalles Bibliográficos
Autores principales: Park, Sun Mi, Baek, Suji, Lee, Jung Hwan, Woo, Sang‐Keun, Lee, Tae Sup, Park, Hyun Soo, Lee, Jongook, Kang, Yeon‐Koo, Kang, Seo Young, Yoo, Min Young, Yoon, Hai‐Jeon, Kim, Bom Sahn, Lee, Kang Pa, Moon, Byung Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10339696/
https://www.ncbi.nlm.nih.gov/pubmed/37038354
http://dx.doi.org/10.1111/cts.13522

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10339696/
https://www.ncbi.nlm.nih.gov/pubmed/37038354
http://dx.doi.org/10.1111/cts.13522

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