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In vivo tissue pharmacokinetics of ERBB2‐specific binding oligonucleotide‐based drugs by PET imaging
Although aptamers have shown excellent target specificity in preclinical and clinical studies either by themselves or as aptamer‐drug conjugates, their in vivo tissue pharmacokinetic (PK) analysis is still problematic. We aimed to examine the utility of image‐based positron emission tomography (PET)...
Autores principales: | Park, Sun Mi, Baek, Suji, Lee, Jung Hwan, Woo, Sang‐Keun, Lee, Tae Sup, Park, Hyun Soo, Lee, Jongook, Kang, Yeon‐Koo, Kang, Seo Young, Yoo, Min Young, Yoon, Hai‐Jeon, Kim, Bom Sahn, Lee, Kang Pa, Moon, Byung Seok |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10339696/ https://www.ncbi.nlm.nih.gov/pubmed/37038354 http://dx.doi.org/10.1111/cts.13522 |
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