Fragment-based drug discovery of small molecule ligands for the human chemokine CCL28

The mucosal chemokine CCL28 is a promising target for immunotherapy drug development due to its elevated expression level in epithelial cells and critical role in creating and maintaining an immunosuppressive tumor microenvironment. Using sulfotyrosine as a probe, NMR chemical shift mapping identifi...

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Detalles Bibliográficos
Autores principales: Zhou, Angela L., Jensen, Davin R., Peterson, Francis C., Thomas, Monica A., Schlimgen, Roman R., Dwinell, Michael B., Smith, Brian C., Volkman, Brian F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10339762/
https://www.ncbi.nlm.nih.gov/pubmed/36841432
http://dx.doi.org/10.1016/j.slasd.2023.02.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10339762/
https://www.ncbi.nlm.nih.gov/pubmed/36841432
http://dx.doi.org/10.1016/j.slasd.2023.02.004

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