Guanidine-modified albumin-MMAE conjugates with enhanced endocytosis ability

Aiming to address the insufficient endocytosis ability of traditional albumin drug conjugates, this paper reports elegant guanidine modification to improve efficacy for the first time. A series of modified albumin drug conjugates were designed and synthesized with different structures, including gua...

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Detalles Bibliográficos
Autores principales: Yi, Ce, Xie, Fei, Xu, Xin, Xiao, Dian, Zhou, Xinbo, Cheng, Maosheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10339779/
https://www.ncbi.nlm.nih.gov/pubmed/37434438
http://dx.doi.org/10.1080/10717544.2023.2219433

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10339779/
https://www.ncbi.nlm.nih.gov/pubmed/37434438
http://dx.doi.org/10.1080/10717544.2023.2219433

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