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Guanidine-modified albumin-MMAE conjugates with enhanced endocytosis ability
Aiming to address the insufficient endocytosis ability of traditional albumin drug conjugates, this paper reports elegant guanidine modification to improve efficacy for the first time. A series of modified albumin drug conjugates were designed and synthesized with different structures, including gua...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10339779/ https://www.ncbi.nlm.nih.gov/pubmed/37434438 http://dx.doi.org/10.1080/10717544.2023.2219433 |