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Simultaneous Determination of the Size and Shape of Single α-Synuclein Oligomers in Solution

[Image: see text] Soluble oligomers of amyloid-forming proteins are implicated as toxic species in the context of several neurodegenerative diseases. Since the size and shape of these oligomers influence their toxicity, their biophysical characterization is essential for a better understanding of th...

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Detalles Bibliográficos
Autores principales: Awasthi, Saurabh, Ying, Cuifeng, Li, Jiali, Mayer, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10339783/
https://www.ncbi.nlm.nih.gov/pubmed/37327131
http://dx.doi.org/10.1021/acsnano.3c01393