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Generation of three induced pluripotent stem cell lines from hypertrophic cardiomyopathy patients carrying MYH7 mutations

MYH7 heterozygous mutations are common genetic causes of hypertrophic cardiomyopathy (HCM). HCM is characterized by hypertrophy of the left ventricle and diastolic dysfunction. We generated three human induced pluripotent stem cell (iPSC) lines from three HCM patients each carrying a single heterozy...

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Detalles Bibliográficos
Autores principales: Cao, Xu, Jahng, James W.S., Lee, Chelsea, Zha, Yanjun, Wheeler, Matthew T., Sallam, Karim, Wu, Joseph C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10339835/
https://www.ncbi.nlm.nih.gov/pubmed/34352619
http://dx.doi.org/10.1016/j.scr.2021.102455