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Regiodivergent synthesis of sulfone-tethered lactam–lactones bearing four contiguous stereocenters

Sulfone-tethered lactones/amides/amines display a diverse spectrum of biological activities, including anti-psychotic and anti-hypertensive. Sulfones are also widely present in functional materials and fragrances. We therefore reasoned that a regiodivergent and stereocontrolled strategy that merges...

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Detalles Bibliográficos
Autores principales: Beng, Timothy K., Eichwald, Jane, Fessenden, Jolyn, Quigley, Kaiden, Sharaf, Sapna, Jeon, Nanju, Do, Minh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10340014/
https://www.ncbi.nlm.nih.gov/pubmed/37456540
http://dx.doi.org/10.1039/d3ra03800a