A novel colchicine-myricetin heterozygous molecule: design, synthesis, and effective evaluations on the pathological models of acute lung injury in vitro and in vivo

Acute lung injury (ALI) is an inflammatory condition and there are no effective treatments. A novel new compound----colchicine-myricetin hybrid (CMyrH) was herein designed and synthesized. To evaluate the activity of CMyrH in ALI, we used a bleomycin (BLM) induced BEAS-2B injury model in vitro and e...

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Detalles Bibliográficos
Autores principales: Li, Zhiyue, Yan, Xueqin, Wei, Jiangchun, Pu, Liuyang, Zhu, Guanbao, Cao, Yongkai, Liu, Zhanyan, Liu, Yaqian, Li, Yan, Li, Limin, Li, Xinping, Wu, Zhengzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10340118/
https://www.ncbi.nlm.nih.gov/pubmed/37456754
http://dx.doi.org/10.3389/fphar.2023.1224906

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10340118/
https://www.ncbi.nlm.nih.gov/pubmed/37456754
http://dx.doi.org/10.3389/fphar.2023.1224906

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