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APOE ε4 allele, along with G206D-PSEN1 mutation, alters mitochondrial networks and their degradation in Alzheimer’s disease

INTRODUCTION: Alzheimer’s disease remains the most common neurodegenerative disorder, depicted mainly by memory loss and the presence in the brain of senile plaques and neurofibrillary tangles. This disease is related to several cellular alterations like the loss of synapses, neuronal death, disrupt...

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Detalles Bibliográficos
Autores principales: Costa-Laparra, Irene, Juárez-Escoto, Elena, Vicario, Carlos, Moratalla, Rosario, García-Sanz, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10340123/
https://www.ncbi.nlm.nih.gov/pubmed/37455931
http://dx.doi.org/10.3389/fnagi.2023.1087072