The Tumor Suppressor DAB2IP Is Regulated by Cell Contact and Contributes to YAP/TAZ Inhibition in Confluent Cells

SIMPLE SUMMARY: External and internal mechanical forces affect the shape, movement, proliferation and metabolism of cells within tissues. The transcriptional regulators YAP and TAZ are key sensors of mechanical inputs, and their aberrant activation in solid tumors promotes cancer aggressiveness. It...

Descripción completa

Detalles Bibliográficos
Autores principales: Apollonio, Mattia, Bellazzo, Arianna, Franco, Nicoletta, Lombardi, Silvia, Senigagliesi, Beatrice, Casalis, Loredana, Parisse, Pietro, Thalhammer, Agnes, Baj, Gabriele, De Florian Fania, Rossella, Del Sal, Giannino, Collavin, Licio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10340159/
https://www.ncbi.nlm.nih.gov/pubmed/37444489
http://dx.doi.org/10.3390/cancers15133379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10340159/
https://www.ncbi.nlm.nih.gov/pubmed/37444489
http://dx.doi.org/10.3390/cancers15133379

Ejemplares similares