Adenovirus-Based Gene Therapy for Bone Regeneration: A Comparative Analysis of In Vivo and Ex Vivo BMP2 Gene Delivery

Adenovirus-mediated gene therapy is a promising tool in bone regenerative medicine. In this work, gene-activated matrices (GAMs) composed of (1) polylactide granules (PLA), which serve as a depot for genetic constructs or matrices for cell attachment, (2) a PRP-based fibrin clot, which is a source o...

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Detalles Bibliográficos
Autores principales: Bukharova, Tatiana Borisovna, Nedorubova, Irina Alekseevna, Mokrousova, Viktoria Olegovna, Meglei, Anastasiia Yurevna, Basina, Viktoriia Pavlovna, Nedorubov, Andrey Anatolevich, Vasilyev, Andrey Vyacheslavovich, Grigoriev, Timofei Evgenevich, Zagoskin, Yuriy Dmitrievich, Chvalun, Sergei Nicolaevich, Kutsev, Sergey Ivanovich, Goldshtein, Dmitry Vadimovich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10340163/
https://www.ncbi.nlm.nih.gov/pubmed/37443796
http://dx.doi.org/10.3390/cells12131762

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10340163/
https://www.ncbi.nlm.nih.gov/pubmed/37443796
http://dx.doi.org/10.3390/cells12131762

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