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TMEM106B Puncta Is Increased in Multiple Sclerosis Plaques, and Reduced Protein in Mice Results in Delayed Lipid Clearance Following CNS Injury

During inflammatory, demyelinating diseases such as multiple sclerosis (MS), inflammation and axonal damage are prevalent early in the course. Axonal damage includes swelling, defects in transport, and failure to clear damaged intracellular proteins, all of which affect recovery and compromise neuro...

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Detalles Bibliográficos
Autores principales: Shafit-Zagardo, Bridget, Sidoli, Simone, Goldman, James E., DuBois, Juwen C., Corboy, John R., Strittmatter, Stephen M., Guzik, Hillary, Edema, Ukuemi, Arackal, Anita G., Botbol, Yair M., Merheb, Emilio, Nagra, Rashed M., Graff, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10340176/
https://www.ncbi.nlm.nih.gov/pubmed/37443768
http://dx.doi.org/10.3390/cells12131734