Bi-Specific Killer Cell Engager Enhances NK Cell Activity against Interleukin-13 Receptor Alpha-2 Positive Gliomas

Glioblastoma (GBM) is a lethal brain tumor with limited therapeutic options. Bi-specific killer cell engagers (BiKEs) are novel immunotherapies designed to engage natural killer (NK) cells against cancer. We designed a BiKE molecule consisting of a single-domain CD16 antibody, an interleukin-15 link...

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Detalles Bibliográficos
Autores principales: Pawlowski, Kristen D., Duffy, Joseph T., Tiwari, Arushi, Zannikou, Markella, Balyasnikova, Irina V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10340194/
https://www.ncbi.nlm.nih.gov/pubmed/37443750
http://dx.doi.org/10.3390/cells12131716

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10340194/
https://www.ncbi.nlm.nih.gov/pubmed/37443750
http://dx.doi.org/10.3390/cells12131716

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