EpoR Activation Stimulates Erythroid Precursor Proliferation by Inducing Phosphorylation of Tyrosine-88 of the CDK-Inhibitor p27(Kip1)

Erythrocyte biogenesis needs to be tightly regulated to secure oxygen transport and control plasma viscosity. The cytokine erythropoietin (Epo) governs erythropoiesis by promoting cell proliferation, differentiation, and survival of erythroid precursor cells. Erythroid differentiation is associated...

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Detalles Bibliográficos
Autores principales: Pegka, Fragka, Ben-Califa, Nathalie, Neumann, Drorit, Jäkel, Heidelinde, Hengst, Ludger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10340229/
https://www.ncbi.nlm.nih.gov/pubmed/37443738
http://dx.doi.org/10.3390/cells12131704

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10340229/
https://www.ncbi.nlm.nih.gov/pubmed/37443738
http://dx.doi.org/10.3390/cells12131704

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