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Fine-Tuning through Generations: Advances in Structure and Production of CAR-T Therapy

SIMPLE SUMMARY: Chimeric antigen receptor (CAR)-T cell therapy has been highly successful in treating hematological malignancies like leukemia and lymphoma, leading to advancements in immunotherapy. The approval of anti-CD19 CAR-T cells by the FDA in 2017 has paved the way for CAR-T therapies to be...

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Detalles Bibliográficos
Autores principales: Zheng, Zhibo, Li, Siyuan, Liu, Mohan, Chen, Chuyan, Zhang, Lu, Zhou, Daobin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10340266/
https://www.ncbi.nlm.nih.gov/pubmed/37444586
http://dx.doi.org/10.3390/cancers15133476