Vitamin D Receptor Antagonist MeTC7 Inhibits PD-L1

SIMPLE SUMMARY: Programmed death-ligand 1 (PD-L1) enables immune evasion of tumors. Antibodies targeting PD-L1/PD-1 exhibit durable responses in eligible patients. However, antibodies cause life-threatening toxicities. Small molecules targeting PD-L1, or the drivers of PD-L1 or PD-L1/PD-1 axis, are...

Descripción completa

Detalles Bibliográficos
Autores principales: Khazan, Negar, Quarato, Emily R., Singh, Niloy A., Snyder, Cameron W. A., Moore, Taylor, Miller, John P., Yasui, Masato, Teramoto, Yuki, Goto, Takuro, Reshi, Sabeeha, Hong, Jennifer, Zhang, Naixin, Pandey, Diya, Srivastava, Priyanka, Morell, Alexandra, Kawano, Hiroki, Kawano, Yuko, Conley, Thomas, Sahasrabudhe, Deepak M., Yano, Naohiro, Miyamoto, Hiroshi, Aljitawi, Omar, Liesveld, Jane, Becker, Michael W., Calvi, Laura M., Zhovmer, Alexander S., Tabdanov, Erdem D., Dokholyan, Nikolay V., Linehan, David C., Hansen, Jeanne N., Gerber, Scott A., Sharon, Ashoke, Khera, Manoj K., Jurutka, Peter W., Rochel, Natacha, Kim, Kyu Kwang, Rowswell-Turner, Rachael B., Singh, Rakesh K., Moore, Richard G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10340436/
https://www.ncbi.nlm.nih.gov/pubmed/37444542
http://dx.doi.org/10.3390/cancers15133432

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10340436/
https://www.ncbi.nlm.nih.gov/pubmed/37444542
http://dx.doi.org/10.3390/cancers15133432

Ejemplares similares