Repeated Social Defeat Stress Induces HMGB1 Nuclear Export in Prefrontal Neurons, Leading to Social Avoidance in Mice

Inflammation has been associated with depression, and innate immune receptors, such as the Toll-like receptor (TLR) 2/4 in the medial prefrontal cortex (mPFC), are crucial for chronic stress-induced depression-related behaviors in mice. HMGB1, a putative ligand for TLR2/4, has been suggested to prom...

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Detalles Bibliográficos
Autores principales: Kitaoka, Shiho, Tomohiro, Ayaka, Ukeshima, Shinya, Liu, Keyue, Wake, Hidenori, Kimura, Shinya H., Yamamoto, Yasuhiko, Nishibori, Masahiro, Furuyashiki, Tomoyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10340449/
https://www.ncbi.nlm.nih.gov/pubmed/37443823
http://dx.doi.org/10.3390/cells12131789

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10340449/
https://www.ncbi.nlm.nih.gov/pubmed/37443823
http://dx.doi.org/10.3390/cells12131789

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