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Thrombin Cleavage of Osteopontin and the Host Anti-Tumor Immune Response

SIMPLE SUMMARY: Osteopontin (OPN) is a protein produced by immune cells, as well as many other cell types including tumor cells, that is highly modified with sugars and phosphates. OPN binds to receptors present on many cell types including cancer and immune cells and causes those cells to change pr...

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Detalles Bibliográficos
Autores principales: Leung, Lawrence L., Myles, Timothy, Morser, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10340489/
https://www.ncbi.nlm.nih.gov/pubmed/37444590
http://dx.doi.org/10.3390/cancers15133480