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MCAK Inhibitors Induce Aneuploidy in Triple-Negative Breast Cancer Models

SIMPLE SUMMARY: Triple-negative breast cancer (TNBC) is the most lethal breast cancer subtype with few treatment options available. Standard of care for TNBC involves the use of taxanes, which are initially effective, but dose limiting toxicities are common and patients often relapse with resistant...

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Detalles Bibliográficos
Autores principales: Smith, John C., Husted, Stefan, Pilrose, Jay, Ems-McClung, Stephanie C., Stout, Jane R., Carpenter, Richard L., Walczak, Claire E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10340532/
https://www.ncbi.nlm.nih.gov/pubmed/37444419
http://dx.doi.org/10.3390/cancers15133309