WDR82-Mediated H3K4me3 Is Associated with Tumor Proliferation and Therapeutic Efficacy in Pediatric High-Grade Gliomas

SIMPLE SUMMARY: Pediatric high-grade gliomas bearing either an H3G34V/R or H3K27M mutation are incurable brain tumors with unique epigenomes. Current epigenomic studies on pHGGs primarily focus on these mutations; however, the function of other important crosstalk histone posttranslational modificat...

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Detalles Bibliográficos
Autores principales: Wadhwani, Nitin, Nayak, Sonali, Wang, Yufen, Hashizume, Rintaro, Jie, Chunfa, Mania-Farnell, Barbara, James, Charles David, Xi, Guifa, Tomita, Tadanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10340597/
https://www.ncbi.nlm.nih.gov/pubmed/37444539
http://dx.doi.org/10.3390/cancers15133429

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10340597/
https://www.ncbi.nlm.nih.gov/pubmed/37444539
http://dx.doi.org/10.3390/cancers15133429

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