CTHRC1 Induces Pancreatic Stellate Cells (PSCs) into Myofibroblast-like Cancer-Associated Fibroblasts (myCAFs)

SIMPLE SUMMARY: CTHRC1 is a protein with pro-tumoral effects that is highly expressed in tumors. We found that cancer stroma is the major source of CTHRC1 secretion in pancreatic cancer, and CTHRC1 regulates cancer extracellular matrix (ECM) remodeling by activating pancreatic stellate cells (PSCs),...

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Detalles Bibliográficos
Autores principales: Kang, Min Kyung, Jiang, Fen, Kim, Ye Ji, Ryu, Kyoungjin, Masamune, Atsushi, Hamada, Shin, Park, Yun-Yong, Koh, Sang Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10340658/
https://www.ncbi.nlm.nih.gov/pubmed/37444482
http://dx.doi.org/10.3390/cancers15133370

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10340658/
https://www.ncbi.nlm.nih.gov/pubmed/37444482
http://dx.doi.org/10.3390/cancers15133370

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