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PRMT-1 and p120-Catenin as EMT Mediators in Osimertinib Resistance in NSCLC

SIMPLE SUMMARY: Non-small-cell lung cancer (NSCLC) patients become resistant to targeted therapies such as tyrosine kinase inhibitors (TKIs) through mutations in the EGFR gene and by overexpression of proteins such as p120-catenin and PRMT-1. We studied EGFR wild-type and mutated EGFR in parental an...

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Detalles Bibliográficos
Autores principales: Racherla, Kavya Sri, Dovalovsky, Katrina, Patel, Meet, Harper, Emma, Barnard, Jacob, Nasifuzzaman, S M, Smith, Mason, Sikand, Riya, Drinka, Eva, Puri, Neelu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10340662/
https://www.ncbi.nlm.nih.gov/pubmed/37444572
http://dx.doi.org/10.3390/cancers15133461