The Highs and Lows of Memantine—An Autophagy and Mitophagy Inducing Agent That Protects Mitochondria

Memantine is an FDA-approved, non-competitive NMDA-receptor antagonist that has been shown to have mitochondrial protective effects, improve cell viability and enhance clearance of Aβ(42) peptide. Currently, there are uncertainties regarding the precise molecular targets as well as the most favourab...

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Detalles Bibliográficos
Autores principales: de Wet, Sholto, Mangali, Asandile, Batt, Richard, Kriel, Jurgen, Vahrmeijer, Nicola, Niehaus, Dana, Theart, Rensu, Loos, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10340721/
https://www.ncbi.nlm.nih.gov/pubmed/37443760
http://dx.doi.org/10.3390/cells12131726

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10340721/
https://www.ncbi.nlm.nih.gov/pubmed/37443760
http://dx.doi.org/10.3390/cells12131726

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